The double slit experiment for a massive scalar particle is described using intuitionistic logic with quantum real numbers as the numerical values of the particle's position and momentum. The model assigns physical reality to single quantum particles. Its truth values are given open subsets of state space interpreted as the ontological conditions of a particle. Each condition determines quantum real number values for all the particle's attributes. Questions, unanswerable in the standard theories, concerning the behaviour of single particles in the (...) experiment are answered. (shrink)

This paper investigates the behavior of conformal fluctuations of space-time geometry that are admissible under the quantized version of Einstein's general relativity. The approach to quantum gravity is via path integrals. It is shown that considerable simplification results when only the conformal degrees of freedom are considered under this scheme, so much so that it is possible to write down a formal kernel in the most general case where the space-time contains arbitrary distributions of particles with no other interaction except (...) gravity. The behavior of this kernel near the classical space-time singularity then shows that quantum fluctuations inevitably diverge near the singularity. It is shown further that the root cause of this divergence lies in the fact that the Green's function for the conformally invariant scalar wave equation diverges at the singularity. The limitations on the validity of classical general relativity near the space-time singularity are discussed and it is argued that the notion of singularity itself needs to be radically modified once the quantum effects are taken into account. (shrink)

In the paper, the multilevel concept of methodology of science is reviewed. The author distinguishes five levels in the methodology of science. These levels vary in degree of generality and the nature of the relationship with philosophy. The first, most general level of the methodology of ways of learning of the studies on the application of science to philosophical methods such as dialectical and metaphysical. The doctrine of general scientific ways of knowing is the second, less common level of methodology (...) of science. The essence of scientific methods is studied at this level, given their theoretical rationale. There are heuristic dignity, epistemological possibilities, and the boundaries of applicability are identified. The third level of the methodology of science is the study of the system of general scientific ways of learning applied in any basic science. In addition to knowledge of the essence of these methods for the researcher requires knowledge of the basic problems of this science. The fourth level of the methodology of science is the study of the system of general scientific ways of learning and epistemological problems in any basic science. The fifth level of the methodology of science are the problems of narrower plan. This study questions the use of certain, specific methods of scientific learning. Thus, the methodology of science is complex and has a complicated structure. The two most general level the methodology are philosophical, the next two are common to philosophy and science, the fifth level is of a specifically scientific nature. (shrink)

The last half century has been characterized by a growth in the regulation of clinical research nationally and internationally. Each area of research on human subjects has been the subject of a vast academic literature and extensive public policy debate, from issues of informed consent to that of regulatory structures. Professor Bernard Dickens has provided an outstanding contribution to this debate internationally through his many innovative and incisive papers in this area. This paper provides an English lawyer’s perspective upon the (...) increasing regulation of clinical research practices and asks – does regulation equate with effective rights protection? From Nuremberg onwards, there has been concern to ensure that research practices are ethical and in accordance with legal principles. So, for example, there have been statements such as the Declaration of Helsinki, which was initially produced in 1964. In the European context in particular, notably influential statements have been the European Convention on Human Rights, which has been followed by the Council of Europe Convention on Human Rights and Biomedicine and, more recently, a Draft Additional Protocol on medical research. (shrink)